Brain Imaging Of Placebo Response
Mechanisms and Methods in Understanding the Placebo Response


Principal Investigator:
W.Vaughn McCall

Investigators and Personnel:
Joseph A. Maldjian, M.D.
Christopher Thomas Whitlow, MD, PhD, MHA

Placebo responses are helpful in routine clinical care, but problematic in clinical trial design. To date, most research in the placebo response has been conducted in pain or Parkinson’s Disease. We will examine the underpinnings of placebo responding in the setting of insomnia treatment, looking for evidence of a ‘universal’ signature brain activity with PET and fMRI .